As Jim Harbaugh stated final yr in preparation for an prolonged highway journey: Deliver the board video games and snacks.

This will probably be an extended journey.

The Chargers will cowl probably the most air miles of any NFL crew in 2025, touring greater than 37,000 miles, in response to Bookies.com. The itinerary begins with a visit to Sao Paulo to face AFC West rival Kansas Metropolis on Sept. 5 within the NFL’s second regular-season sport performed in South America.

The season opener is the primary of three consecutive divisional video games to kick off the Chargers’ second yr beneath Harbaugh. The AFC West added former Seahawks and USC coach Pete Carroll in Las Vegas, the place the Chargers will play at 7 p.m. PDT on Sept. 15 in a “Monday Night Football” showcase. It’s certainly one of 5 prime-time video games for the Chargers.

Making an attempt to make consecutive postseason appearances for the primary time since 2009, the Chargers first must confront ghosts of playoffs previous. They’ve rematches towards their final two playoff opponents as Houston visits SoFi Stadium in Week 17 and the Chargers go to Jacksonville on Nov. 16. The reminiscence of a blown 27-point lead within the 2022 wild-card sport possible gained’t absolutely fade till the crew will get over the postseason hump beneath Harbaugh and quarterback Justin Herbert.

Along with the Corridor of Fame Sport on July 31, the Chargers will play preseason video games at SoFi Stadium towards the New Orleans Saints (Aug. 10) and the Rams (Aug. 16). They shut the preseason towards the San Francisco 49ers on the highway (date to be decided).

Right here’s a game-by-game have a look at the regular-season schedule (all instances Pacific).

Sept. 5, KANSAS CITY in Sao Paulo, Brazil, 5 p.m. (YouTube): Maybe one other change of surroundings may help break the Chargers’ 11-game residence dropping streak on this sequence. Kansas Metropolis’s highway dominance spans three cities and 4 stadiums with wins in San Diego, StubHub Middle, Mexico Metropolis’s Estadio Azteca and SoFi Stadium for the reason that Chargers’ final residence win within the sequence in 2013.

Sept. 15, at Las Vegas, 7 p.m. (ESPN): As if this division rivalry wanted extra gasoline. Greater than a decade after they battled within the NFC West and the Pac-12, Jim Harbaugh and Pete Carroll meet once more on “Monday Night Football.”

Sept. 21, DENVER, 1:05 p.m. (CBS): The Chargers’ residence win over the Broncos final season not solely arrange a late-season surge, however it achieved a life-long objective for Harbaugh. He received to witness Cameron Dicker hit the longest honest catch free kick in NFL historical past.

Sept. 28, at New York Giants, 10 a.m. (CBS): The Chargers get their first have a look at Malik Nabers, however the Giants star second-year receiver is already a well-known face for Chargers second-round choose Tre’ Harris. Harris, a receiver out of Mississippi, was Nabers’ highschool quarterback in Lafayette, La.

New York Giants huge receiver Malik Nabers runs with the ball towards the Indianapolis Colts in December.

(Corey Sipkin / Related Press)

Oct. 5, WASHINGTON, 1:25 p.m. (Fox): San Bernardino native Jayden Daniels will play his first NFL sport in L.A. after profitable the NFL offensive rookie of the yr and main the Commanders to their first look within the NFC championship sport since 1991.

Oct. 12, at Miami, 10 a.m. (CBS): The Dolphins haven’t gained a playoff sport since 2000, the longest lively postseason victory drought within the NFL.

Oct. 19, INDIANAPOLIS, 1:05 p.m. (CBS): The Colts have by no means performed at SoFi Stadium and have the longest playoff drought of any of the Chargers’ 2025 opponents, not making the postseason since 2020.

Oct. 23, MINNESOTA, 5:15 p.m. (Prime Video): The Vikings’ presumptive starter J.J. McCarthy will face off towards his former coach. McCarthy, who led Michigan to a nationwide title beneath Harbaugh in 2023, missed his rookie season due to a knee harm.

Nov. 2, at Tennessee, 10 a.m. (CBS): No. 1 total choose Cam Ward will attempt to elevate the crew that hasn’t made the playoffs since 2021. The Chargers haven’t gained a highway sport at Tennessee since 2009, dropping 3 times by a mixed margin of 9 factors.

Nov. 9, PITTSBURGH, 5:20 p.m. (NBC): With no playoff win since 2016, the Steelers are nonetheless ready for a choice from 41-year-old Aaron Rodgers to find out who will throw passes to key offseason acquisition D.Ok. Metcalf.

Nov. 16, at Jacksonville, 10 a.m. (CBS): Of their notorious wild card collapse in Jacksonville, the Chargers turned the primary NFL crew to lose a playoff sport with a turnover differential of plus-five or higher.

Nov. 23, off week

Nov. 30, LAS VEGAS, 1:25 p.m. (CBS): With Carroll and former Seahawks quarterback Geno Smith in Las Vegas, the AFC West may once more be one of the vital aggressive divisions within the NFL after three groups made it to the playoffs final yr.

Dec. 8, Philadelphia, 5:15 p.m. (ABC/ESPN): The Chargers upgraded the dimensions on their inside defensive position to arrange for matchups like this one. The Tremendous Bowl champions’ dominance on the line of scrimmage is the usual for the league.

Dec. 14, at Kansas Metropolis, 10 a.m. (CBS): The Chargers have misplaced seven consecutive video games to their AFC West rivals with six coming by seven factors or fewer together with final yr’s nail-biter at Arrowhead Stadium that ended with the Chiefs hitting a game-winning discipline objective off the upright.

Dec. 21, at Dallas, 10 a.m. (Fox): After a contract extension that paid an NFL-record $60 million a yr, Dak Prescott had a career-low 86.0 passer ranking whereas throwing 11 touchdowns with eight passes intercepted earlier than lacking 10 video games due to a hamstring harm.

Week 17, HOUSTON, TBD: Herbert can redeem himself towards the protection that grabbed 4 interceptions within the Chargers’ 2024 playoff flop. Texans quarterback and Rancho Cucamonga native C.J. Stroud returns to his Southern California roots.

Week 18, at Denver, TBD: The Chargers secured their first win in Denver since 2018 final season.